🩸 Physician use only. Hematologic emergencies require real-time labs (CBC, coags, peripheral smear, type & screen), specialist co-management, and institutional blood bank coordination. Dosing requires adjustment for weight, renal function, and clinical context.  ·  Evidence: A = RCT/meta-analysis · B = cohort/expert consensus  ·  Severity: Critical = life-threatening · Severe = hospitalization likely · Moderate = close monitoring · Mild = outpatient